Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0313735
PubChem CID
Molecular Formula
C11H10N2OS
Molecular Weight
218.281 g/mol
Synonyms/Alias
[N-(4-methylthiazol-2-yl)benzamide; 37529-67-2; N-(4-methyl-1;3-thiazol-2-yl)benzamide; CHEMBL209410; N-(4-Methyl-thiazol-2-yl)-benzamide; Enamine_001521; TimTec1_007096; MLS001212480; N6QHC7G324; SCH...
InChI Key
NEPIZAVYXKHUCD-UHFFFAOYSA-N
InChI
InChI=1S/C11H10N2OS/c1-8-7-15-11(12-8)13-10(14)9-5-3-2-4-6-9/h2-7H,1H3,(H,12,13,14)
IUPAC Name
N-(4-methyl-1,3-thiazol-2-yl)benzamide
CAS Number
185103-81-5

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

25 26 0 0 0 0 0 0 0 0999 V2000
4.8191 1.0886 -0.0062 C 0 0 0 0 0 0 0 0 0 0 0 0
3.7963 0.0048 0.0864 C 0 0 0 0 0 0 0 0 0 0 0 0
4.1290 -1.335...

Experimental Data

Activity Data

Target Ion Channel
Cystic fibrosis transmembrane conductance regulator (Chloride channel) (detaF508-CFTR)
Uniprot Accession Number
Function
Inactive
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
No effect

Experimental Conditions

pH
pH 7.5
Holding Potential
Not specified
Temperature
37 °C
Test Method
Fluorometric Imaging Plate Reader (FLIPR) Membrane Potential Assay
Test Species
A549 cell

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
15
Rotatable Bonds
2
logP
2.7038
Complexity
61.2462
TPSA (Ų)
41.99
H-Bond Donors
1
H-Bond Acceptors
3
Ring Count
2
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